Characterization of in vitro antagonistic activity of Lactobacillus helveticus DLBSA201 and DLBSA202 against Escherichia coli 0157:H7
نویسندگان
چکیده
Lactobacillus helveticus DLBSA201 and DLBSA202 were investigated for their potential probiotic traits protective effects against Escherichia coli O157:H7. The survival rate of after being exposed to acid bile salt was relatively high, although no hydrolase activity detected. Both strains also demonstrated an outstanding ability adhere intestinal epithelial cells. A combination could interfere with the growth E. Furthermore, exhibited remove pre-adhered O157:H7 on Those able lower pro-inflammatory genes [TLR-4, tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8)] in lipopolysaccharides (LPS)-treated In addition, upregulation occludin ZO-1 by ameliorates disruption barrier caused LPS. above results suggest that association appear as promising candidates prevent treat disease
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ژورنال
عنوان ژورنال: Food Science and Technology
سال: 2023
ISSN: ['2331-513X', '2331-5156']
DOI: https://doi.org/10.5327/fst.129522